";s:4:"text";s:3533:" Enteral—Entering Intestinal/Digestive Tract. a. Different dosage forms are available for the administration orally. Oral administration (PO), ingestion of a drug by mouth and into the gastrointestinal tract, is one way by which a drug can be taken. Routes of Drug Administration 1. 1.0 INTRODUCTION Today various routs available for the administration of drugs but the oral route is the simplest and most preferable route for the administration of dosage forms. This is the most frequently used route of drug administration and is the most convenient and cost-effective. Oral Drug Use. It might be: Oral; Sublingual; Per rectum; Photo by Slashme. lignocaine) - unconscious patients. These advantages include safety, good patient compliance, ease of ingestion, pain avoidance, and versatility to accommodate various types of drugs ( Sastry et al., 2000 ). - drugs with extensive first pass metabolism (e.g. - drugs that are destroyed by digestive juices (e.g. Oral route has a slow onset of action, hence not used in emergency. Oral Route: Oral route is the most common route of drug administration. The oral administration route is preferred over the various other administration routes of drug delivery due to the many advantages it exhibits.
The oral route of administration gave a significantly higher serum peak concentration compared with the vaginal route, but there was no difference if water was added to the tablets. Emulsion suspensions 4.
aminoglycosides). Oral. a) Oral route - This is the most common and easiest route of administration where drugs are given by mouth. Oral administration (PO), ... Another kind of route of drug administration is known as transdermal, or through the skin. Enteral Route: Enteral route is through the alimentary canal. Advantages: It is convenient Capsules 3.
It is mostly used for the neutral drugs. Different routes are Oral route, sublingual route, rectal route, parentral routes, subcutaneous, intravenous, Intramuscular.
Disadvantages of the oral route of administration include the relatively slow onset of action, the possibilities of irregular absorption, the destruction of acid-labile drugs in the stomach, and the unsuitability of this route for many high-molecular-weight drugs. It may be in the form of tablets, capsules, syrup, emulsions or powders. Although solid-dose forms such as tablets and capsules have a high degree of drug stability and provide accurate dosage, the oral route is problematic because of the unpredictable nature of gastrointestinal absorption. The time to peak concentration was significantly shorter in the sublingual and oral groups than in either of the two vaginal routes of administration. ORAL ROUTE Advantages Safer Cheaper Painless Convenient for repeated and prolonged use. 1. Most drugs are absorbed from small intestine but some are absorbed from stomach and colon.
PO stands for per os , or by mouth. It is not suitable for/in- - unpalatable and highly irritant drugs.